FEATURES OF HISTOLOGICAL STRUCTURE AND DIFFERENTIAL DIAGNOSTICS OF THE DIFFUSE-TYPE GIANT CELL TUMOR AND ITS MALIGNANT FORM.

Features of histological structure and differential diagnostics of the diffuse-type giant cell tumor and its malignant form.

Background.Tenosynovial giant cell tumor of diffuse type is one of the most widespread tumor of joints, causing destruction of the soft tissues and bone articular surfaces.Objective.The purpose of the study was to formulate approaches here to histological differential diagnostics between diffuse-type giant cell tumor and its malignant forms.Methods

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Long interspersed nuclear element-1 hypomethylation and oxidative stress: correlation and bladder cancer diagnostic potential.

Although, increased oxidative stress and hypomethylation of long interspersed nuclear element-1 (LINE-1) associate with bladder cancer (BCa) development, the relationship between these alterations is unknown.We evaluated the oxidative stress and hypomethylation of the LINE-1 in 61 BCa patients and 45 normal individuals.To measure the methylation le

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In Vivo Imaging of Cobalt-Induced Ocular Toxicity in a Mouse Model

Cobalt is a trace element, crucial for red blood cell formation and neurological function.Cobalt toxicity is often only diagnosed after severe manifestations, including visual impairment.We aimed to investigate whether optical coherence tomography (OCT) and magnetic resonance read more imaging (MRI) can effectively detect cobalt-induced ocular toxi

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